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Response of Drosophila metallothionein promoters to metallic, heat shock and oxidative stresses
Author(s) -
Bonneton François,
Théodore Laurent,
Silar Philippe,
Maroni Gustavo,
Wegnez Maurice
Publication year - 1996
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(95)01544-2
Subject(s) - drosophila melanogaster , metallothionein , promoter , transgene , gene , reporter gene , microbiology and biotechnology , oxidative phosphorylation , chemistry , biology , gene expression , biochemistry
The metallothionein system in Drosophila melanogaster is composed of two genes, Mtn and Mto . In order to compare the induction properties of these genes, we transformed D. melanogaster with P ‐element vectors containing Adh and lacZ reporter genes under the control of Mtn and Mto promoters, respectively. Mtn and Mto transgenes are mainly expressed in the digestive tract. However, Mtn expression has been detected also in the fat body. Mtn and Mto transgenes respond differently to metallic, heat‐shock and oxidative stresses. These data confirm that both genes are in part functionally different.