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Characterization of an Arabidopsis thaliana cDNA homologue to animal poly(ADP‐ribose) polymerase
Author(s) -
Loïc Lepiniec,
Elena Babiychuk,
Sergeï Kushnir,
Marc Van Montagu,
Dirk Inzé
Publication year - 1995
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(95)00335-7
Subject(s) - arabidopsis , arabidopsis thaliana , complementary dna , biology , polymerase , gene , microbiology and biotechnology , poly adp ribose polymerase , dna , genetics , mutant
A full‐length Arabidopsis thaliana cDNA ( app ) encoding a protein with high similarity (about 60%) to the catalytic domain of vertebrate poly(ADP‐ribose) polymerase (PARP; EC 2.4.2.30) has been cloned. The N‐terminal extension of the Arabidopsis protein shows similarities with domains of different nuclear and DNA binding proteins in agreement with nuclear localization and putative function of a plant PARP. APP is encoded by a single gene mapped at the top of chromosome 4 of the Arabidopsis genome and mRNA is abundant in cell suspension culture compared to its accumulation in whole plant.