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DNA replication specificity of TYLCV geminivirus is mediated by the amino‐terminal 116 amino acids of the Rep protein
Author(s) -
Jupin Isabelle,
Hericourt François,
Benz Bianca,
Gronenborn Bruno
Publication year - 1995
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(95)00221-t
Subject(s) - terminal (telecommunication) , amino acid , biology , dna replication , dna , amino terminal , virology , replication (statistics) , genetics , peptide sequence , gene , computer science , telecommunications
Geminiviruses are plant DNA viruses replicating by a rolling circle mechanism. We have investigated the specificity of replication origin recognition of two different isolates of tomato yellow leaf curl virus (TYLCV). Here, we show that TYLCV‐Sardinian and ‐Israeli replication proteins display a high degree of specificity for their respective origins. The DNA sequences recognized are located on the left part of the intergenic region whereas the amino‐terminal 116 amino acids of the Rep protein determine the specificity of origin recognition.