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ATP/ADP antiporter is involved in uncoupling of plant mitochondria induced by low concentrations of palmitate
Author(s) -
Vianello A.,
Petrussa E.,
Macrì F.
Publication year - 1994
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(94)00712-8
Subject(s) - antiporter , mitochondrion , uncoupling protein , chemistry , atp–adp translocase , biochemistry , microbiology and biotechnology , biophysics , biology , inner mitochondrial membrane , membrane , adipose tissue , brown adipose tissue
Carboxyatractyloside partially restored the transmembrane electrical potential difference (ΔΨ) dissipated by low concentrations of palmitate in pea stem mitochondria. This effect was more marked when mitochondria from sunflower were assayed. It is suggested that the ATP/ADP translocator is involved in the free fatty acid‐induced uncoupling of oxidative phosphorylation in plant mitochondria, only when its level is sufficiently high and the concentration of the fatty acid is low to collapse only partially the ΔΨ.