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Atomic force microscope of bacteriophage T4 and its tube‐baseplate complex
Author(s) -
Ikai Atsushi,
Yoshimura Kousei,
Arisaka Fumio,
Ritani Akishige,
Imai Kensaku
Publication year - 1993
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(93)81756-p
Subject(s) - atomic force microscopy , wafer , resolution (logic) , bacteriophage , materials science , microscope , tube (container) , microscopy , optics , silicon , nanotechnology , chemistry , physics , optoelectronics , composite material , escherichia coli , biochemistry , artificial intelligence , computer science , gene
Bacteriophage T4 was imaged by atomic force microscopy with the finest resolution to date with a clear image of tail fibers of an estimated diameter of 2–3 nm. T4 phages were spread on a clean surface of silicon wafer and dried under air before observation with an atomic force microscope. The head, tail and tail fibers were routinely imaged with somewhat distorted dimensions. The ease of imaging isolated phage particles with a good resolution raised our expectation for the further use of AFM in biomedical applications.