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The local information content of the protein structural database
Author(s) -
Rao Srikar,
Zhu Qing-Lin,
Vajda Sandor,
Smith Temple
Publication year - 1993
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(93)81555-e
Subject(s) - protein structure database , simple (philosophy) , sequence (biology) , protein structure , computer science , content (measure theory) , database , information retrieval , computational biology , chemistry , biology , mathematics , sequence database , biochemistry , mathematical analysis , philosophy , epistemology , gene
A simple study of the information available within proteins of known structure reveals both the limits of structure prediction based on overall statistical correlations between sequence and structure, and the areas where there is still a possibility for further structural database exploitation.