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Multiple genes for G protein‐coupled receptors and their expression in lingual epithelia
Author(s) -
Abe Keiko,
Kusakabe Yuko,
Tanemura Kentaro,
Emori Yasufumi,
Arai Soichi
Publication year - 1993
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(93)81302-g
Subject(s) - receptor , gene , biology , polymerase chain reaction , microbiology and biotechnology , transmembrane protein , transmembrane domain , gene expression , g protein coupled receptor , genetics
Using the polymerase chain reaction (PCR), we identified a gene family including more than 60 members which encoded similar G protein‐coupled seven‐transmembrane receptors. Sequence analyses of six representatives out of the 60 PCR clones showed that they had significant structural similarity to olfactory and optic receptors. Their expression is restricted in the surface of lingual epithelia.