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The effect of annexin IV and VI on the fluidity of phosphatidylserine/phosphatidylcholine bilayers studied with the use of 5‐deoxylstearate spin label
Author(s) -
Sobota Andrzej,
Bandorowicz Joanna,
Jezierski Adam,
Sikorski Aleksander F.
Publication year - 1993
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(93)81158-v
Subject(s) - phosphatidylserine , phosphatidylcholine , annexin , chemistry , membrane fluidity , membrane , biophysics , spin label , biochemistry , chromatography , phospholipid , in vitro , biology
An effect of annexin IV and VI on the fluidity of phosphatidylserine/phosphatidylcholine (PS/PC) membranes was studied by spin labeling technique with the use of 5‐doxylstearic acid. It was found that calcium ions at micromolar concentrations induced a marked decrease in the order parameter of PS/PC membranes. This effect was completely abolished by both annexins. The influence of annexins on the mobility of fatty acid chains in the studied region in PE/PC membranes was insignificant.