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Cloning of CRP2, a novel member of the cysteine‐rich protein family with two repeats of an unusual LIM/double zinc‐finger motif
Author(s) -
Okano Ichiro,
Yamamoto Takeshi,
Kaji Akira,
Kimura Toru,
Mizuno Kensaku,
Nakamura Toshikazu
Publication year - 1993
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(93)80373-3
Subject(s) - zinc finger , complementary dna , lim domain , coding region , tandem repeat , cysteine , cloning (programming) , chemistry , microbiology and biotechnology , gene , biology , genetics , biochemistry , genome , transcription factor , enzyme , computer science , programming language
The cDNA coding for a novel member of the cysteine‐rich protein family was isolated from a rat brain cDNA library. It encodes a protein, denoted cysteine‐rich protein 2 (CRP2), of 208 amino acid residues containing two tandem repeats of an unusual LIM/double zinc‐finger‐like motif. The ubiquitous tissue distribution and high level of expression of CRP2 mRNA suggest an important role for CRP2 in cell functions.