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Ankyrin‐like proteins of variola and vaccinia viruses
Author(s) -
Shchelkunov Sergei N.,
Blinov Vladimir M.,
Sandakhchiev Lev S.
Publication year - 1993
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(93)80059-4
Subject(s) - vaccinia , variola virus , virology , ankyrin , smallpox , poxviridae , biology , chemistry , biochemistry , vaccination , recombinant dna , gene
Computer analysis of full coding sequences of variola major virus strain India‐1967 genome and vaccinia virus strain Copenhagen genome have been carried out. A wide set of proteins containing ankyrin‐like repeats have been identified for both viruses. Only three proteins of this family of the studied viruses are highly homologous. The rest of the proteins are different. The possible role of such proteins in determination of virus tissue tropism is discussed.