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Half‐life of ubiquinone‐9 in rat tissues
Author(s) -
Thelin Anders,
Schedin Sophia,
Dallner Gustav
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)81425-l
Subject(s) - chemistry , kidney , half life , endocrinology , medicine , biochemistry , biology , pharmacokinetics
The half‐life of ubiquinone‐9 in various rat tissues was determined. Rats were injected intraperitoneally with [ 3 H]mevalonate and the decay of radioactivity incorporated into ubiquinone‐9 was followed using reverse‐phase HPLC. The half‐life varied between 49 h (testis) and 125 h (kidney).