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Evidence for a hydroxy‐aluminium polymer (Al 13 ) in synaptosomes
Author(s) -
Rao Gazula Valeswara,
Rao K.S.Jagannatha
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)81364-r
Subject(s) - aluminium , dysprosium , synaptosome , polymer , reagent , chemistry , nuclear chemistry , inorganic chemistry , analytical chemistry (journal) , chromatography , organic chemistry , calcium
The presence of the hydroxy‐aluminium polymer (Al 13 ‐(OH) 24 O 4 (H 2 O) 7+ 12 ) was noticed inside synaptosomes when synaptosomes were incubated with Al(NO 3 ) 3 at neutral pH values. Dysprosium nitrate (Dy(NO 3 )3) ‐ a shift reagent ‐ facilitates the identification of the Al 13 species distinctly inside the synaptosomes. 27 Al NMR was used as a tool to detect the Al 13 complex inside and outside the synaptosomes.