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Parathyroid hormone activation of stretch‐activated cation channels in osteosarcoma cells (UMR‐106.01)
Author(s) -
Duncan Randall L.,
Hruska Keith A.,
Misler Stanley
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)80771-8
Subject(s) - parathyroid hormone , conductance , chemistry , membrane , osteoblast , biophysics , hormone , membrane potential , medicine , microbiology and biotechnology , endocrinology , biochemistry , biology , calcium , in vitro , physics , organic chemistry , condensed matter physics
Cell‐attached patches of membrane of osteoblast‐like cells UMR‐106.01 respond to bath application of parathyroid hormone (PTH) with an increase in the average activity, as well as the single channel conductance, of a stretch‐activated non‐selective cation channel. Correlations with whole cell membrane potential and conductance changes are considered.