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Caf1R gene and its role in the regulation of capsule formation of Y. pestis
Author(s) -
Karlyshev A.V.,
Galyov E.E.,
Abramov V.M.,
Zav'yalov V.P.
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)80650-6
Subject(s) - open reading frame , gene , gene cluster , dna , homology (biology) , genetics , biology , gene product , regulator gene , transcription (linguistics) , dna sequencing , base pair , microbiology and biotechnology , regulation of gene expression , peptide sequence , gene expression , linguistics , philosophy
A new transcription unit of the f1 gene cluster was found. The DNA sequencing revealed one long open reading frame. Deletion and frame shift mutation analyses have demonstrated the importance of a corresponding gene product for the F1 antigen biosynthesis. A homology of the deduced amino acid sequence with that of AraC family DNA‐binding regulators was shown. A potential regulatory DNA region is discussed.