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α‐Amylases and approaches leading to their enhanced stability
Author(s) -
Janeček Štefan,
Baláž Štefan
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)80575-2
Subject(s) - extremophile , mesophile , amylase , enzyme , chemistry , biochemical engineering , biochemistry , biology , thermophile , engineering , genetics , bacteria
The recent state of the knowledge of properties and structure of α‐amylases is reviewed with the aim of elucidation the basis for their stabilization. Three principal ways for obtaining stable α‐amylases (isolation of enzymes from extremophiles, production of extremophilic enzymes in mesophiles, and modification of mesophilic enzymes) are discussed separately. Detailed experimental examples are given for modification approaches.