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‘ box A’‐like sequence between the 16 S/23 S spacer in rRNA operon of mycoplasmas
Author(s) -
Harasawa R.,
Uemori T.,
Asada K.,
Kato I.,
Shiragami N.
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)80539-s
Subject(s) - operon , ribosomal rna , sequence (biology) , genetics , internal transcribed spacer , biology , spacer dna , nucleic acid sequence , intergenic region , gene , genome , escherichia coli
We have found that a boxA ‐like sequence is conserved in the 16 S and 23 S rRNA intergenic spacer regions of mycoplasmas, and that it always locates on loop regions of the hypothetical secondary stem‐loop structures. A nucleotide sequence similar to the ‘−10’ box of prokaryotic promoters was identified at upstream sites of the boxA ‐like sequence in the 16 S/23 S spacer regions. These structures may represent an internal promoter between the 16 S and 23 S rRNA genes in mycoplasmas.