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Mode of sodium ion action on methanogenesis and ATPase of the moderate halophilic methanogenis bacterium Methanohalophilus halophilus
Author(s) -
Šmigán̆ Peter,
Rusn̆ák Peter,
Greksák Miloslav,
Zhilina Tatja.,
Zavarzin Georgij A.
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)80194-l
Subject(s) - monensin , chemistry , sodium , methylamine , antiporter , divalent , methanogenesis , membrane , atpase , ion , ion transporter , ammonium , nuclear chemistry , inorganic chemistry , biochemistry , biophysics , methane , enzyme , biology , organic chemistry
Cells of Methanohalophilus halophilus swelled when exposed to hypotonic solutions of NaCl at pH 7.0. The swelling of the cells ceased in the presence of Mg 2+ . Methane formation by non‐growing cells was strongly dependent on the NaCl concentration. Among other monovalent and divalent cations only Li + and Mg 2+ could partly substitute for a specific function of sodium ions. The artificial Na + /H + antiporter, monensin, exerted a strong inhibitory effect on methane formation from methylamine. The membrane‐bound Mg 2+ ‐stimulated ATPase of these cells was enhanced at low (40 mM) NaCl concentration while higher concentrations of this solute were inhibitory. The results obtained show that sodium ions are a prerequisite for optimal methane formation and ATPase activity in these cells. However, both of these processes required different sodium ion concentrations.

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