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A novel super‐secondary structure of β‐proteins A triple‐strand corner
Author(s) -
Efimov A.V.
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)80072-o
Subject(s) - triple helix , chemistry , biophysics , computational biology , biology , stereochemistry
A novel super‐secondary structure of β‐proteins, denoted here as a triple‐strand corner, is considered in this paper. This structure can be represented as an antiparallel triple‐strand β‐sheet folded on itself so that the two β‐β‐hairpins are packed approximately orthogonally in different layers and the central strand bends by 90° in the right‐handed direction when passing from one layer to the other. In all the triple‐strand corners observed in proteins, the first β‐β‐hairpins are right‐handed and the second ones are left‐handed when viewed from the concave sides of the corners. Arrangement of other β‐strands in the proteins involving the triple‐strand corners is also examined.