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Ordered binding model as a general mechanistic mechanism for secondary active transport systems
Author(s) -
Yamato Ichiro
Publication year - 1992
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(92)80008-5
Subject(s) - mechanism (biology) , chemistry , biophysics , active site , energy transport , coupling (piping) , biochemistry , biology , materials science , enzyme , physics , engineering physics , quantum mechanics , metallurgy
The mechanistic mechanism of secondary active transport processes has not been fully elucidated. Based on substrate binding, studies dependent on coupling cation concentrations of the glutamate, melibiose, lactose and proline transport carriers in Escherichia coli , the ordered binding mechanism was proposed as the energy coupling mechanism of the transport systems. This ordered binding mechanism satisfactorily explained the properties of the secondary active transport systems. Thus, this mechanism as the general energy coupling mechanism for the transport systems is discussed.