Premium
Purification and characterization of a Kunitz‐type trypsin inhibitor from Leaf‐nosed viper venom
Author(s) -
Siddiqi Abdur Rehman,
Zaidi Zafar H.,
Jörnvall Hans
Publication year - 1991
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(91)81361-b
Subject(s) - viper venoms , venom , viper , trypsin , proteases , trypsin inhibitor , kunitz sti protease inhibitor , snake venom , chemistry , biochemistry , biology , enzyme
A Kunitz‐type trypsin inhibitor was purified from Leaf‐nosed viper venom and the primary structure determined by peptide analysis. In relation to other trypsin inhibitors, the protein has an extended C‐terminal segment and a distinct pattern of residue alterations at the functionally important contact sites with proteases.