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Reactions of the α‐tocopheroxyl radical in micellar solutions studied by nanosecond laser flash photolysis
Author(s) -
Bisby Roger H.,
Parker Anthony W.
Publication year - 1991
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(91)81260-f
Subject(s) - flash photolysis , photodissociation , photochemistry , nanosecond , chemistry , flash (photography) , laser , micellar solutions , micelle , optics , organic chemistry , aqueous solution , kinetics , physics , reaction rate constant , quantum mechanics
Laser flash photolysis of α‐tocopherol in methanol and in aqueous micellar solutions has been shown to produce the α‐tocopheroxyl radical. The reaction between the α‐tocopheroxyl radical and ascorbate in positively charged hexadecyltrimethylammonium chloride (HTAC) micelles occurred with a second order rate constant of 7.2 × 10 7 M −1 ·s −1 , whereas in negatively charged sodium dodecyl sulphate (SDS) micelles the rats constant was only 3.8 × 10 4 M −1 ·s −1 . The α‐tocopheroxyl radical was found to be relatively long‐lived in HTAC micelles ( t ½ ⩾ 5 min), allowing the slow disappearance of the α‐tocopheroxyl radical by reaction with glutathione to be observed.