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Chondroitinases release acetylcholinesterase from chick skeletal muscle
Author(s) -
Pérez-Tur Jordi,
Barat Ana,
Ramos Milagros,
Ramirez Galo
Publication year - 1991
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(91)80932-s
Subject(s) - acetylcholinesterase , dermatan sulfate , basal lamina , heparan sulfate , skeletal muscle , heparin , glycosaminoglycan , chemistry , aché , chondroitin sulfate , biochemistry , microbiology and biotechnology , biophysics , anatomy , biology , enzyme , ultrastructure
Bacterial chondroitinases (both ABC and AC types) release asymmetric and globular forms of AChE from chick skeletal muscle samples. Heparinases, however, including heparitinase I, fail to do so under different incubation conditions. These results do not support the direct implication of the heparin/heparan sulfate family of GAGs in the interaction of the different AChE molecular forms with the muscle ECM. GAGs of the chondroitin/dermatan sulfate group could however be involved, either directly or indirectly, in the attachment of the AChE collagen‐like tail to the muscle basal lamina.