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The effect of F 0 inhibitors on the Vibrio alginolyticus membrane ATPase
Author(s) -
Capozza G.,
Dmitriev O.Yu.,
Krasnoselskaya I.A.,
Papa S.,
Skulachev V.P.
Publication year - 1991
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(91)80310-y
Subject(s) - vibrio alginolyticus , atpase , chemistry , enzyme , membrane , vesicle , biochemistry , vibrio , bacteria , biology , genetics
The inhibition of membrane ATPase from the marine alkalotolerant bacterium Vibrio alginolyticus by DCCD, triphenyltin and venturicidin was studied. DCCD proved to be an irreversible inhibitor, while venturicidin and triphenyltin produced a reversible inhibitory effect. The DCCD‐binding proteolipid was identified in the membrane preparations. The effect of the inhibitors on ATPase activity and ATP‐dependent Na + ‐transport in V. alginolyticus subcellular vesicles is discussed.