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Molecular resolution imaging of polyglucose by scanning tunneling microscopy
Author(s) -
Yang Jie,
Takeyasu Kunio,
Somlyo Andrew P.,
Shao Zhifeng
Publication year - 1991
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(91)80171-x
Subject(s) - microscopy , scanning tunneling microscope , resolution (logic) , scanning confocal electron microscopy , scanning ion conductance microscopy , nanotechnology , materials science , chemistry , biophysics , optics , physics , biology , computer science , artificial intelligence
We have obtained atomic resolution images of poly‐α‐D‐glucose by scanning tunneling microscopy. The oxygen atoms near the scanning tip were imaged, but the carbon and hydrogen atoms were not visible. The measured inter‐atomic distances are consistent with the molecular structure of poly‐α‐D‐glucose deduced from chemical and X‐ray diffraction studies. The results also demonstrate that is 1% feasible to image surface atomic structures of a relatively thick non‐conducting specimen, suggesting that the technique may be applied to the study of other macromolecules of biological importance.