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Effect of removal of zinc on alfalfa mosaic virus RNA‐dependent RNA polymerase
Author(s) -
R. Quadt,
E.M.J. Jaspars
Publication year - 1991
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(91)80083-f
Subject(s) - rna , virology , rna polymerase , rna dependent rna polymerase , alfalfa mosaic virus , zinc finger , virus , biology , zinc , polymerase , microbiology and biotechnology , coat protein , chemistry , gene , biochemistry , transcription factor , organic chemistry
The necessity of coat protein for infection of plants by alfalfa mosaic virus (AIMV) and other ilarviruses distinguishes this virus group from other plants virus groups, Recently, the presence of both a zinc‐finger type motif and zinc in AIMV coat protein was described [(1989) Virology 168, 45–56]. We studied the effect of a zinc chelator on viral RNA synthesis. Strong inhibition of AIMV RNA‐dependent RNA polymerase (RdRp) by ortho‐phenanthroline (OP) was observed.