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How do viral reverse transcriptases recognize their RNA genome?
Author(s) -
Mesnard Jean-Michel,
Lebeurier Geneviéve
Publication year - 1991
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(91)80002-k
Subject(s) - reverse transcriptase , retrotransposon , biology , genome , rna , genetics , transcription (linguistics) , dna , transposable element , gene , linguistics , philosophy
Reverse transcription is not solely a retroviral mechanism. Hepadnaviruses and caulimoviruses have RNA intermediates that are reverse transcribed into DNA. Moreover non‐viral retroelements, retrotransposons, use reverse transcription in their transposition. All these retroelements encode reverse transcriptase but each group developed their own expression modes capable of assuring a specific and efficient replication of their genomes.