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Interaction of benzoquinones with mitochondria interferes with oxidative phosphorylation characteristics
Author(s) -
Makawiti Dominic W.,
Konji Victor N.,
Olowookere Julius O.
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)81497-c
Subject(s) - oxidative phosphorylation , juglone , mitochondrion , phosphorylation , chemistry , electron transport chain , biochemistry
Studies with four benzoquinones, viz. juglone, embelin, maesaquinone and maesanin, on rat liver mitochondria oxidative phosphorylation have been carried out. Three of the benzoquinones are uncouplers in the order juglone > maesoquinone > embelin, while maesanin is an inhibitor of electron transport and oxidative phosphorylation.