Premium
Regulation of plant gene expression by antisense RNA
Author(s) -
Mol J.N.M.,
van der Krol A.R.,
van Tunen A.J.,
van Blokland R.,
de Lange P.,
Stuitje A.R.
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)81298-3
Subject(s) - antisense rna , sense (electronics) , gene , biology , rna , gene expression , rna silencing , genetics , function (biology) , regulation of gene expression , computational biology , microbiology and biotechnology , rna interference , chemistry
Regulation of gene expression by antisense RNA was first discovered as a naturally‐occurring phenomenon in bacteria. Recently natural antisense RNAs have been found in a variety of eukaryotic organisms; their in vivo function is, however, obscure. Deliberate expression of antisense RNA in animal and plant systems has lead to successful down‐regulation of specific genes. We will review the current status of antisense gene action in plant systems. The recent discovery that ‘sense’ genes are able to mimic the action of antisense genes indicates that (anti)sense genes must operate by mechanisms other than RNA‐RNA interaction.