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mRNA acetylated at 2'‐OH‐groups of ribose residues is functionally active in the cell‐free translation system from wheat embryos
Author(s) -
Ovodov S.Yu.,
Alakhov Yu.B.
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)81246-k
Subject(s) - acetylation , ribonuclease , messenger rna , translation (biology) , cell free system , chemistry , ribose , biochemistry , bovine pancreatic ribonuclease , embryo , pancreatic ribonuclease , chemical modification , microbiology and biotechnology , enzyme , biology , rna , gene
Modification (acetylation) of 2'‐OH groups of mRNA ribose residues does not result in a loss of their template activity in a cell‐free translation system from wheat embryos and in some cases activates inactive mRNAs. Modification of 70–75% of 2'‐OH groups makes mRNA stable to the effect of pancreatic ribonuclease.