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Primary structure of cAMP‐gated channel from bovine olfactory epithelium
Author(s) -
Ludwig Jost,
Margalit Talya,
Eismann Elisabeth,
Lancet Doron,
Kaupp U.Benjamin
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)81226-e
Subject(s) - olfactory epithelium , cyclic nucleotide gated ion channel , protein primary structure , complementary dna , peptide sequence , biology , nucleic acid sequence , cloning (programming) , olfactory system , microbiology and biotechnology , chemistry , nucleotide , biochemistry , cyclic nucleotide , gene , neuroscience , computer science , programming language
The complete amino‐acid sequence of the bovine olfactory epithelium adenosine 3',5'cyclic monophosphate (cAMP)‐gated channel has been determined by cloning and sequencing its cDNA. It exhibits a high degree of sequence homology with the cGMP‐gated channel of rod photoreceptors, suggesting that cyclic nucleotide‐gated channels fall into a new family of genetically related proteins.