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Slipping pumps or proton leaks in oxidative phosphorylation
Author(s) -
van Dam Karel,
Shinohara Yasuo,
Unami Akira,
Yoshida Kenji,
Terada Hiroshi
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)80826-5
Subject(s) - slipping , oxidative phosphorylation , cytochrome c oxidase , proton pump , chemistry , proton , biophysics , mitochondrion , biochemistry , biology , physics , enzyme , engineering , quantum mechanics , atpase , mechanical engineering
Evidence is presented to show that the local anesthetic bupivacaine causes slip in the mitochondrial proton pump cytochrome c oxidase.

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