Premium
Photosystem I reaction‐centre proteins contain leucine zipper motifs
Author(s) -
Webber Andrew N.,
Malkin Richard
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)80749-9
Subject(s) - leucine zipper , bzip domain , basic helix loop helix leucine zipper transcription factors , zipper , leucine , cysteine , atf3 , chemistry , amino acid , biochemistry , photosystem i , peptide sequence , biology , photosystem ii , gene , dna binding protein , transcription factor , enzyme , gene expression , promoter , photosynthesis , algorithm , computer science
The photosystem I (PS I) reaction‐centre polypeptides, encoded by the psa A and psa B genes, are shown to contain several highly conserved leucine repeats, consisting of a leucine residue every seventh amino acid, similar to the leucine zipper motifs known to mediate DNA‐binding polypeptide dimerisation. In each of the PSI reaction‐centre subunits the leucine zipper motif precedes highly conserved cysteine residues which have been proposed to ligate the interpolypeptide [4Fe‐4S] centre, Fx. We propose that PS I reaction‐centre dimerisation and [4Fe‐4S] centre formation are mediated through the leucine zipper.