Premium
Cloning and nucleotide sequence of cDNA for retinochrome, retinal photoisomerase from the squid retina
Author(s) -
Hara-Nishimura Ikuko,
Matsumoto Tetsunori,
Mori Hitoshi,
Nishimura Mikio,
Hara Reiko,
Hara Tomiyuki
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)80383-t
Subject(s) - rhodopsin , complementary dna , biology , nucleic acid sequence , coding region , homology (biology) , squid , transmembrane domain , nucleotide , cloning (programming) , retinal , genetics , gene , biochemistry , fishery , computer science , programming language
The Rhodopsin‐retinochrome system is essential for the visual photoreception of molluscs. cDNA coding for retinochrome of the squid ( Todarodes pacificus ) was cloned and the nucleotide sequence has been determined. The sequence (2.1 kb) covers the whole coding region of 903 bp. The deduced primary sequence suggests that retinochrome contains seven transmembrane spanning domains. The homology with bovine rhodopsin and the possible retinal binding site are also discussed.