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Characterization of N ‐cadherin mRNA in chicken brain and heart by means of oligonucleotide probes
Author(s) -
Dalseg Anne-Marie,
Andersson Anna-Maria,
Bock Elisabeth
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)80198-r
Subject(s) - oligonucleotide , messenger rna , microbiology and biotechnology , chemistry , biology , computational biology , biochemistry , gene
It has previously been reported, that there is only one mRNA of 4.3 kb for chicken N ‐cadherin in brain and heart and one gene [(1988) J. Cell Biol. 106, 873‐881]. Using three synthetic oligonucleotide probes derived from the published chicken N ‐cadherin cDNA sequence we found hybridization to at least four mRNAs in chicken brain and heart. The measured sizes were 8.0, 4.7, 3.8, and 3.3 kb. The 8.0 kb mRNA is only seen in brain, and only when a cytoplasmic probe is employed. The 3.8 kb mRNA is only observed in heart.