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A second consensus sequence of ATP‐requiring proteins resides in the 21‐kDa C‐terminal segment of myosin subfragment 1
Author(s) -
Burke Morris,
Rajasekharan Kallikat N.,
Maruta Shinsaku,
Ikebe Mitsuo
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)80185-l
Subject(s) - myosin , consensus sequence , terminal (telecommunication) , sequence (biology) , nucleotide , biology , biochemistry , peptide sequence , myosin light chain kinase , gene , computer science , telecommunications
Previous comparisons of sequence homologies of ATP‐requiring enzymes have defined three consensus sequences which appear to be involved in the binding of the nucleotide. One of these was identified in the N‐terminal 27‐kDa segment of the myosin heavy chain but the other two sequences have not hitherto been located in myosin. The present paper proposes that one of these other two consensus sequences is in the 21‐kDa C‐terminal portion of S1 and that it may contribute to the ATP binding domain.