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Evidence for a molten globule state as a general intermediate in protein folding
Author(s) -
Ptitsyn O.B.,
Pain R.H.,
Semisotnov G.V.,
Zerovnik E.,
Razgulyaev O.I.
Publication year - 1990
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(90)80143-7
Subject(s) - molten globule , protein folding , folding (dsp implementation) , chemistry , state (computer science) , biophysics , folding funnel , crystallography , phi value analysis , downhill folding , biochemistry , computer science , biology , engineering , algorithm , electrical engineering
We propose that the formation of the transient molten globule state occurs early on the pathway of folding of all globular proteins.