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Scapharca hemoglobins, type cases of a novel mode of chain assembly and heme‐heme communication
Author(s) -
Petruzzelli Raffaele,
Boffi Alberto,
Barra Donatella,
Bossa Francesco,
Ascoli Franca,
Chiancone Emilia
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)81512-1
Subject(s) - heme , chemistry , biochemistry , biology , microbiology and biotechnology , enzyme
The sequences of the A and B chains of the Scapharca inaequivalvis tetrameric hemoglobin (HbII) are reported. They are homologous to the corresponding chains of other Arcid hemoglobins. Moreover, a comparison of the present data with the sequence of the S. inaequivalvis dimeric hemoglobin (HbI), for which high‐resolution X‐ray data are available, allows the identification of the residues that direct the assembly of the two components and of those that may be involved in the interdimeric contacts.