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Fructose 2,6‐bisphosphate and glucose 1,6‐bisphosphate levels in erythrocytes with high and low 2,3‐bisphosphoglycerate content during postnatal development
Author(s) -
Gallego Carme,
Carreras José
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)81431-0
Subject(s) - fructose 2,6 bisphosphate , phosphofructokinase , pyruvate kinase , fructose , biochemistry , glycolysis , phosphatase , chemistry , biology , enzyme
In rabbit and sheep erythrocytes the concentrations of 2,3‐bisphosphoglycerate, fructose 2,6‐bisphosphate and glucose 1,6‐bisphosphate suffer important changes after birth, which differ in both species. The changes of fructose 2,6‐bisphosphate and glucose 1,6‐bisphosphate correlate with the changes in the levels of the enzymatic activities involved in their synthesis. The change of 2,3‐bisphosphoglycerate levels in rabbit but not in sheep erythrocytes could be explained by the changes of the phosphofructokinase/pyruvate kinase and 2,3‐bisphosphoglycerate synthase/2,3‐bisphosphoglycerate phosphatase activity ratios.