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Remarks on the supramolecular organization of the glycolytic system in vivo
Author(s) -
Batke J.
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)81419-x
Subject(s) - glycolysis , in vivo , enzyme , flux (metallurgy) , in vitro , chemistry , intracellular , biochemistry , biophysics , supramolecular chemistry , microbiology and biotechnology , biology , crystallography , genetics , organic chemistry , crystal structure
The great latent catalytic capacity, manifested at the extremely high intracellular concentrations and in large apparent k cat / K m values, of the glycolytic enzymes on the one hand and their tendency in experiments in vitro to form functionally‐specific flux‐enhancing (channeling) complexes on the other, is considered and discussed as an apparent discrepancy. A random association of glycolytic enzymes in vivo is probable.