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Human platelets release α‐6‐L‐fucosyltransferase upon activation
Author(s) -
Antoniewicz J.,
Bykowska K.,
Zdebska E.,
Kościelak J.
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)80569-1
Subject(s) - fucosyltransferase , platelet , coagulation , glycoconjugate , chemistry , enzyme , human blood , platelet activation , biochemistry , immunology , biology , medicine , physiology
Previously we have shown that human platelets release α‐6‐L‐fucosyltransferase (EC 2.4.1.68) during coagulation of blood [(1987) Glycoconjugate J. 4, 43–49]. Here we report that agonists which induce platelet aggregation bring about release of the enzyme. In quantitative terms the release of α‐6‐L‐fucosyltransferase by washed, aggregated platelets was very similar to that occurring during blood coagulation.