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The structure and properties of horse muscle acylphosphatase in solution Mobility of antigenic and active site regions
Author(s) -
Saudek Vladimir,
Williams Robert J.P.,
Ramponi Giampietro
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)80474-0
Subject(s) - antigenicity , chemistry , nuclear magnetic resonance spectroscopy , protein structure , active site , amino acid , biochemistry , antigen , biology , stereochemistry , catalysis , genetics
The solution structure of acylphosphatase determined by proton nuclear magnetic resonance spectroscopy is described. The results allow us to discuss the fold of the protein (101 amino acids), to correlate the exposure and the mobility of the backbone with the antigenicity, and to locate the active site.