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87 Rb NMR studies of the perfused rat heart
Author(s) -
Allis Jonathan L.,
Snaith Christine D.,
Seymour Anne-Marie L.,
Radda George K.
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)80472-7
Subject(s) - chemistry , radiochemistry , nuclear magnetic resonance , physics
We have studied 87 Rb + fluxes in the perfused rat heart using nuclear magnetic resonance spectroscopy (NMR). A simple model for the interpretation of the data is presented. A comparison of radioactively measured K + fluxes and the K + fluxes deduced from the 87 Rb + measurements shows them to be very similar. This method provides a means of noninvasively measuring uni‐directional K + fluxes in the heart.