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A barley flour inhibitor of insect α‐amylase is a major allergen associated with baker's asthma disease
Author(s) -
Barber Domingo,
Sánchez-Monge Rosa,
Gómez Luis,
Carpizo José,
Armentia Alicia,
López-Otín Carlos,
Juan Fernando,
Salcedo Gabriel
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)80444-2
Subject(s) - allergen , trypsin inhibitor , amylase , trypsin , biochemistry , chemistry , insect , immunoglobulin e , enzyme , peptide sequence , asthma , allergy , food science , biology , botany , antibody , immunology , gene
A barley salt‐soluble protein of 14.5 kDa, which inhibits the α‐amylase from the insect Tenebrio molitor , has been identified as a major IgE‐binding component of sera from baker's asthma patients. The N‐terminal amino acid sequence of this protein indicates that it is a member of a previously described family of α‐amylase/trypsin inhibitors.