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The expression of genes coding for positive acute‐phase proteins in the reproductive tract of the female rat
Author(s) -
Thomas Tim,
Schreiber Gerhard
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)80166-8
Subject(s) - ceruloplasmin , decidua , uterus , biology , glycoprotein , medicine , endocrinology , messenger rna , andrology , gestation , fetus , alpha (finance) , decidual cells , gene , acute phase protein , pregnancy , placenta , microbiology and biotechnology , immunology , biochemistry , genetics , inflammation , construct validity , nursing , patient satisfaction
High levels of ceruloplasmin mRNA were measured in the uterus of both pregnant and non‐pregnant rats. No mRNA for α 2 ‐macroglobulin and α 1 ‐acid glycoprotein could be detected in the uterus in contrast to the high levels of those two mRNAs found in the decidua in the mid‐gestation period. Synthesis of plasma proteins with a protective function in the decidua or uterus may be important in maintaining homeostasis at different stages of reproduction. In addition, ceruloplasmin synthesis by the uterus may be part of a system transporting copper to the fetus.