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Electrostimulation‐induced fast‐to‐slow transitions of myosin light and heavy chains in rabbit fast‐twitch muscle at the mRNA level
Author(s) -
Kirschbaum Bernhard J.,
Heilig Annegard,
Härtner Karl-Thomas,
Pette Dirk
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)80112-7
Subject(s) - myosin , messenger rna , stimulation , rabbit (cipher) , myosin light chain kinase , immunoglobulin light chain , chemistry , fast twitch muscle , biophysics , biology , endocrinology , medicine , skeletal muscle , biochemistry , gene , genetics , statistics , mathematics , antibody
Chronic low‐frequency stimulation of rabbit fast‐twitch muscle induces progressive increases in slow myosin light chain mRNAs followed by an increase in the slow myosin heavy chain HCI mRNA. Therefore, the effects of chronic stimulation are more pronounced in rabbit than in rat fast‐twitch muscle. The latter responds mainly with a rearrangement of its fast isomyosin pattern.