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Three actin‐binding proteins are developmentally regulated in rat liver plasma membranes
Author(s) -
Keresztes Margit
Publication year - 1989
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(89)80013-4
Subject(s) - actin , membrane , microbiology and biotechnology , chemistry , biophysics , biochemistry , biology
Actin‐binding membrane proteins (linking microfilaments to the cell membrane) are involved in cytoskeleton‐membrane interactions which are supposed to undergo profound changes during cell proliferation and development. In this study 8 polypeptides were shown to bind F‐actin directly in the liver cell membranes of mature rats. From these, the abundance of three polypeptides, of 130, 50 and 36 kDa, was observed to increase considerably during postnatal development, which indicates a developmental change in the cytoskeleton‐membrane interactions.