Premium
Phospholipid flippases
Author(s) -
Devaux Philippe F.
Publication year - 1988
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(88)81291-2
Subject(s) - endoplasmic reticulum , phospholipid , membrane , chemistry , chromosomal translocation , phospholipid scramblase , cell membrane , biophysics , phosphatidylserine , microbiology and biotechnology , biochemistry , biology , gene
Protein mediated phospholipid translocation through membranes has been observed in rat liver endoplasmic reticulum and in the plasma membrane of erythrocytes as well as in a few other cell membranes. Lipid translocation in plasma membranes is ATP dependent and selectively accumulates aminophospholipids on the inner monolayers.