Premium
Potassium channels expressed from rat brain cDNA have delayed rectifier properties
Author(s) -
Stühmer Walter,
Stocker Martin,
Sakmann Bert,
Seeburg Peter,
Baumann Arnd,
Grupe Andrew,
Pongs Olaf
Publication year - 1988
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(88)81015-9
Subject(s) - complementary dna , xenopus , potassium channel , inward rectifier potassium ion channel , microbiology and biotechnology , rna , chemistry , biology , biophysics , biochemistry , gene , ion channel , receptor
Injection into Xenopus oocytes of RNA synthesized in vitro using the rat brain cDNA RCK1 as a template or nuclear injection of the cDNA results in the expression of functional potassium channels. These channels exhibit properties similar to those of the non‐inactivating delayed rectifier channel found in mammalian neurons and other excitable cells.