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Murine mRNA for the β‐subunit of integrin is increased in BALB/c‐3T3 cells entering the G 1 phase from the G 0 state
Author(s) -
Tominaga Shin-ichi
Publication year - 1988
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(88)80503-9
Subject(s) - microbiology and biotechnology , messenger rna , integrin , 3t3 cells , protein subunit , basal (medicine) , biology , stimulation , chemistry , cell , cell culture , endocrinology , biochemistry , transfection , gene , genetics , insulin
The amount of murine mRNA for the β‐subunit of integrin is enriched 6‐fold when BALB/c‐3T3 cells traverse from the G 0 state to the G 1 phase, whereas it remains at the basal level when the cells are growing continuously. The peak of its appearance is at 10 h after serum stimulation. The increase in integrin mRNA at a specific point in cell proliferation may be correlated with growth‐signal transduction.