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K + channels activated by L‐alanine transport in isolated Necturus enterocytes
Author(s) -
Sheppard D.N.,
Giraldez F.,
Sepúlveda F.V.
Publication year - 1988
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(88)80134-0
Subject(s) - necturus , chemistry , alanine , biophysics , enterocyte , biochemistry , biology , amino acid , small intestine , intracellular
Using the patch‐clamp technique, we demonstrate here the opening of K + channels evoked by the actively transported amino acid L‐alanine in isolated Necturus enterocytes. These channels had a conductance of about 30 pS and their activation was dependent on transmembrane electrical potential and cytosolic Ca 2+ .